Which condition is a predisposition for CLABSI?

Which condition is a predisposition for CLABSI?

• A. Young, Healthy Adults With No Comorbidity
• B. Immunocompromised States
• C. Short Hospital Stay
• D. Adequate Nutrition

Answer: (B)

Immunocompromised states raise the risk of CLABSI because a central line can become a route for skin or environmental organisms to enter the bloodstream, and a weakened immune system struggles to contain or eradicate them. When the immune defenses are diminished—such as with chemotherapy-induced neutropenia, advanced HIV, organ transplantation on immunosuppressants, or chronic steroid use—the likelihood that colonizing organisms progress to bloodstream infection increases. In contrast, being young and healthy, having a short hospital stay, or having adequate nutrition all support better defense against infection, reducing the chance of CLABSI rather than predisposing to it.

Immunocompromised states raise the risk of CLABSI because a central line can become a route for skin or environmental organisms to enter the bloodstream, and a weakened immune system struggles to contain or eradicate them. When the immune defenses are diminished—such as with chemotherapy-induced neutropenia, advanced HIV, organ transplantation on immunosuppressants, or chronic steroid use—the likelihood that colonizing organisms progress to bloodstream infection increases. In contrast, being young and healthy, having a short hospital stay, or having adequate nutrition all support better defense against infection, reducing the chance of CLABSI rather than predisposing to it.